Hormones and Eczema: What's the Connection?

By Diane Angela Fong, ND & Rachel Lucke, MS, CNS, LDN

Eczema is more than just a skin condition; it’s a signal from your body that something deeper may be going on. While many are familiar with the role of allergens, stress, and environmental factors in triggering eczema, the influence of hormones is often overlooked. But could the ebb and flow of your hormones be contributing to those frustrating flare-ups?

In this blog, we'll explore the connection between hormones and eczema, diving into how hormonal imbalances and changes can impact your skin and potentially exacerbate this chronic condition. Understanding this link could be the key to addressing the root cause of your eczema symptoms more effectively.

Understanding the Connection Between Hormones and Eczema

Hormones are chemical messengers that regulate many functions in the body, including metabolism, immune response, and skin health. Imbalances in hormone levels can disrupt these processes, potentially exacerbating eczema symptoms. 

Sex Hormones

Menstrual Cycle Fluctuations

Many people with eczema report that their symptoms worsen during specific phases of their menstrual cycle. This can be attributed to changes in estrogen and progesterone levels. These hormonal fluctuations may affect the skin’s hydration and barrier function, leading to increased dryness and irritation.

During the menstrual cycle, levels of estrogen and progesterone fluctuate significantly. Estrogen, which peaks in the middle of the cycle, is known for its skin-rejuvenating properties. It promotes collagen production and helps maintain skin hydration. Conversely, progesterone, which increases in the latter half of the cycle, can have a drying effect on the skin, potentially exacerbating eczema symptoms. For individuals with irregular cycles, these hormonal shifts can be unpredictable, leading to inconsistent skin responses.

Irregular menstrual cycles can cause unpredictable hormonal fluctuations, leading to fluctuating levels of estrogen and progesterone. This unpredictability can make it challenging to manage eczema, as the skin’s response to hormonal changes becomes less predictable. For instance, someone with irregular cycles might experience exacerbations of eczema during times when progesterone levels are higher, leading to increased dryness and irritation.

Irregular menstrual cycles can be indicative of underlying conditions such as polycystic ovary syndrome (PCOS) or thyroid disorders, which themselves can influence eczema. PCOS, for example, often leads to higher levels of androgens (male hormones) and insulin resistance, both of which can affect skin health and inflammation. Similarly, thyroid imbalances can impact skin hydration and immune function, further complicating eczema management.

Pregnancy

Pregnancy induces significant hormonal changes that can either improve or worsen eczema. Some people experience an improvement in their symptoms due to the increased levels of progesterone, which has anti-inflammatory properties. Conversely, others may find that their eczema worsens due to changes in estrogen and overall immune system alterations during pregnancy.

Perimenopause & Menopause

Menopause is a natural biological process marking the end of a person’s menstrual cycles, typically occurring in the late 40s to early 50s. This transition is accompanied by a significant drop in estrogen levels, which can impact various aspects of health, including skin condition. For people with eczema, menopause can present unique challenges and exacerbate symptoms. 

One of the most notable changes during menopause is the decline in estrogen levels. Estrogen plays a crucial role in maintaining skin health by promoting collagen production, skin hydration, and elasticity. Reduced estrogen levels lead to decreased skin hydration and barrier function. This can result in drier skin, which is more prone to eczema flare-ups. Dry, cracked skin can further irritate the eczema-affected areas, making symptoms worse. Estrogen is essential for maintaining skin thickness and elasticity. Lower levels of estrogen during menopause can cause the skin to become thinner and less resilient. Thinner skin is more easily irritated and inflamed, which can aggravate eczema symptoms. Estrogen also influences the immune system, and its decline can affect immune responses. Since eczema is an inflammatory skin condition, changes in immune function can potentially exacerbate symptoms or lead to increased susceptibility to flare-ups. The combination of drier, thinner skin and altered immune responses can contribute to more frequent and severe eczema flare-ups. Women may notice increased itching, redness, and inflammation during and after the transition into menopause.

While estrogen levels decrease, progesterone levels can fluctuate, especially in the perimenopausal period in the decade leading up to menopause. During perimenopause, the ovaries are gradually producing less progesterone and estrogen, and the hormonal balance is shifting. Progesterone production begins to decline more noticeably as a woman approaches menopause. This drop can lead to irregular menstrual cycles, with periods becoming shorter or longer, and sometimes heavier or lighter. Lower progesterone levels can contribute to symptoms such as irregular bleeding, mood swings, hot flashes, and sleep disturbances.

By menopause, which is defined as 12 consecutive months without a menstrual period, progesterone levels are significantly reduced. This is because the ovaries stop releasing eggs, and thus, progesterone production drops dramatically. With the significant reduction in progesterone, estrogen can dominate, which may lead to symptoms like hot flashes, night sweats, and vaginal dryness. In postmenopause, the ovaries produce very low levels of hormones compared to before, and progesterone is produced in minimal amounts, mainly from the adrenal glands.

These hormonal changes during perimenopause and menopause can alter the skin's sensitivity, making it more reactive to environmental factors such as allergens, irritants, and temperature changes. This heightened sensitivity can exacerbate eczema symptoms.

Thyroid Hormones

Thyroid imbalances, such as those seen in hypothyroidism or hyperthyroidism, can influence skin health. Hypothyroidism, for example, can lead to dry, flaky skin, which can aggravate eczema. Proper thyroid function is crucial for maintaining healthy skin and immune response.

Thyroid hormones play a critical role in regulating the body's metabolism, energy levels, and overall health. They also have significant effects on skin health. Disruptions in thyroid function, whether due to hypothyroidism (underactive thyroid) or hyperthyroidism (overactive thyroid), can impact eczema in various ways. Here’s a detailed look at how thyroid imbalances affect eczema and what you can do to manage it.

Understanding Thyroid Hormones

The thyroid gland, located in the neck, produces hormones such as thyroxine (T4) and triiodothyronine (T3). These hormones regulate metabolism, energy levels, and many other physiological processes, including skin health. Hypothyroidism occurs when the thyroid gland underproduces thyroid hormones. This condition can lead to a range of symptoms, including fatigue, weight gain, cold intolerance, and dry skin. Hyperthyroidism is characterized by an overproduction of thyroid hormones. Symptoms include weight loss, rapid heartbeat, heat intolerance, and sometimes, changes in skin texture.

Effects of Hypothyroidism on Eczema

One of the hallmark symptoms of hypothyroidism is dry, rough skin. The thyroid hormones play a crucial role in maintaining skin hydration and elasticity. Low levels of these hormones can lead to a compromised skin barrier, making it more prone to dryness and irritation. This can exacerbate eczema symptoms, leading to increased itching and flare-ups. Hypothyroidism can cause thickening of the skin, known as myxedema. This thickening can lead to more severe eczema symptoms as the skin becomes less flexible and more prone to cracking and irritation. Individuals with hypothyroidism may experience slower skin healing processes. This can delay the resolution of eczema flare-ups and prolong periods of discomfort and inflammation. Hypothyroidism often leads to increased sensitivity to cold temperatures. Cold, dry air can further dehydrate the skin and aggravate eczema symptoms.

Effects of Hyperthyroidism on Eczema

Hyperthyroidism can lead to increased sweating and oily skin. Excess sweat and oil can contribute to clogged pores and exacerbate eczema, particularly in areas prone to sweating. Hyperthyroidism can result in thinning of the skin. Thin skin is more susceptible to damage and irritation, which can worsen eczema symptoms. Elevated levels of thyroid hormones can lead to increased skin inflammation and sensitivity. This heightened inflammatory response can aggravate eczema, leading to more severe flare-ups and discomfort. People with hyperthyroidism often experience heat intolerance, which can lead to sweating and increased skin irritation. This can trigger or worsen eczema symptoms, particularly in hot or humid environments.

Stress Hormones

Stress affects the body’s hormone levels, particularly cortisol. Cortisol is a hormone released in response to stress, and its imbalance can impact the immune system and inflammatory responses. High levels of cortisol can lead to increased inflammation, potentially worsening eczema symptoms.

Managing Hormones and Eczema

Understanding the relationship between hormones and eczema can help in managing the condition more effectively. Here are some strategies to consider:

Track Hormonal Changes

Keeping a diary of your eczema flare-ups alongside menstrual cycles or other hormonal changes can help identify patterns. This information can be useful for managing symptoms aand discussing potential treatments with a healthcare provider.

Manage Stress

Stress is a common factor contributing to both irregular menstrual cycles and eczema flare-ups. Stress affects cortisol levels, which can influence skin inflammation and immune response. Additionally, stress-induced hormonal imbalances can make menstrual cycles more irregular, creating a cycle of exacerbating eczema symptoms. Incorporating stress-reducing techniques such as mindfulness, exercise, and relaxation practices can help manage cortisol levels and potentially improve eczema symptoms.

Eat a Balanced Diet

A balanced diet that supports overall health can influence hormone levels and skin health. Consider including foods rich in omega-3 fatty acids, antioxidants, and vitamins that support skin integrity and immune function.  A diet rich in essential fatty acids, antioxidants, and vitamins can support overall skin health and help regulate hormone levels. Consider including foods that promote skin hydration and reduce inflammation.

Get Tested for Hormonal Imbalances

When you work with one of our Cleanbody Practitioners, we may recommend certain lab testing to assess your hormones. Hormone testing can use blood, saliva, and/or urine and can often be done in the comfort of your home.

Avoid Endocrine-Disrupting Chemicals

Exposure to endocrine-disrupting chemicals (EDCs) can significantly impact hormones and disrupt the normal functioning of the endocrine system, which regulates various physiological processes in the body. EDCs affect the body in a number of ways.

Some EDCs can mimic the action of natural hormones by binding to hormone receptors. For example, certain EDCs might mimic estrogen, a key hormone involved in reproductive and developmental processes. When these chemicals bind to estrogen receptors, they can trigger responses similar to those caused by actual estrogen, leading to overstimulation or disruption of normal hormonal balance. EDCs can also block hormones from binding to their receptors. For instance, if an EDC binds to a receptor that would normally be occupied by thyroid hormone, it can prevent the thyroid hormone from carrying out its regulatory functions. This blockage can interfere with processes controlled by thyroid hormones, such as metabolism and growth.

EDCs can also affect the production and release of hormones. They might interfere with the synthesis of hormones by disrupting the glands that produce them, such as the thyroid, adrenal glands, or gonads. For example, some EDCs can inhibit the enzymes needed to produce thyroid hormones, leading to hypothyroidism. EDCs can influence how hormones are metabolized and broken down. By affecting the enzymes responsible for hormone metabolism, these chemicals can lead to either excessive accumulation or insufficient levels of certain hormones in the body. The endocrine system relies on feedback loops to maintain hormonal balance. EDCs can interfere with these feedback mechanisms, leading to imbalances. For example, if an EDC disrupts the feedback loop involving the hypothalamus and pituitary gland, it can result in abnormal levels of hormones being released.

EDCs can have particularly profound effects on developmental and reproductive hormones. Exposure during critical periods of development, such as in utero or during puberty, can lead to long-term effects on reproductive health, fertility, and sexual development. For instance, exposure to certain EDCs has been linked to early onset of puberty, reproductive disorders, and developmental abnormalities. Long-term exposure to EDCs has been associated with an increased risk of various chronic diseases, including cancer, metabolic disorders (like obesity and diabetes), and cardiovascular conditions. This is partly because hormonal imbalances can disrupt metabolic processes and cellular functions.

Overall, the impact of endocrine-disrupting chemicals on hormones is complex and can lead to a wide range of health effects, from immediate symptoms to long-term chronic conditions. The more exposure to these chemicals, the more work your drainage organs have to do to try to keep your Cleanbody Funnel flowing. Reducing exposure to known EDCs and understanding their effects are important for maintaining hormonal and overall health.

Support Your Drainage Organs

Your body's drainage organs, including the liver, kidneys, lymphatic system, and gut, play a crucial role in eliminating toxins and waste products. When these organs aren't working optimally, this can contribute to hormone imbalances. By joining our Essential Support Membership, you'll gain access to protocols designed to cleanse and support each of these drainage organs. Through our programs, we offer comprehensive tests to assess the functioning of your drainage organs, allowing for individualized support to optimize detoxification pathways and promote overall wellness.

Understanding Drainage Organs​

• Liver: The liver acts as your body's primary detoxification organ, filtering toxins and hormone metabolites from the bloodstream and producing bile to aid in digestion and waste elimination.

• Kidneys: Kidneys filter waste products and excess fluids from the blood, excreting them in the form of urine to maintain electrolyte balance and regulate blood pressure.

• Lymphatic System: The lymphatic system helps remove cellular waste, toxins, and pathogens from the body, supporting immune function and fluid balance.

• Gut: The gut plays a vital role in detoxification by breaking down and absorbing nutrients while preventing the absorption of toxins and waste products. A healthy gut microbiome is essential for proper digestion, immune function, and toxin elimination.

Optimize your body's natural detoxification pathways with our CleanSKIN Drainage Kit. Specially designed to support the gut and liver, this kit promotes effective drainage and toxin elimination, which are essential for maintaining healthy skin. Each supplement in this kit is formulated to enhance your body's ability to process and remove toxins, reducing the burden on your skin.

CleanSKIN Drainage Kit

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Seek Professional Guidance

Consulting with our team can provide personalized guidance and support on your journey to better lifestyle choices. Our team at Cleanbody offers one-on-one consultations with Dr. Fong and Cleanbody Nutritionists to assess your individual needs, develop tailored nutrition plans, and address any underlying health issues contributing to poor nutrition. Attend Dr. Fong's next live Q&A session every Wednesday to ask questions, or schedule a consultation to start your journey towards optimal health.

Hormone imbalances can play a significant role in the exacerbation of eczema symptoms, influencing factors such as inflammation, hydration, and immune response. By understanding how hormonal fluctuations affect eczema, individuals can better manage their condition and work with healthcare professionals to develop a comprehensive treatment plan. Remember, effective management involves a combination of addressing hormonal issues, maintaining skin health, and adopting a holistic approach to wellness.

Questions?

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References

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About the Authors:

Dr. Diane Angela Fong, ND, is the CEO and founder of Cleanbody, a wellness company dedicated to treating and preventing chronic disease. She is the creator of the Cleanbody Method, which follows a three-step process: Evaluate (digging into the root causes of chronic disease using lab testing and other evaluation tools), Optimize (enhancing health foundations by addressing nutrition, lifestyle, and toxic exposures), and Support (optimizing organ functions through healing protocols).

Rachel Lucke, MS, CNS, LDN is a Cleanbody Practitioner and Nutritionist specializing in meeting people in their healthy journeys by digging into the root causes of various chronic diseases and conditions. Through the use of healthy food along with aspects of the natural world around us (sunshine, nature, clean water, stress management, relationships, etc), she helps to empower her clients to take charge of their own health and trust their bodies to thrive and heal.

Medical Disclaimer: The information provided in this blog post is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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