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Navigating a Healing Crisis in Eczema Treatment

By Dr. Diane Angela Fong, ND



Healing eczema isn’t always a straightforward journey. As you work to address the root causes of your symptoms—whether it’s gut imbalances, toxins, or underlying infections—you may experience a temporary worsening of your condition known as a Herxheimer reaction or “healing crisis.” While this reaction can feel frustrating or even alarming, it’s often a sign that your body is actively working to eliminate harmful substances and restore balance.


The good news is that there are steps you can take to minimize these reactions and make your healing journey more comfortable. Gradually introducing treatments, supporting your detox pathways, staying hydrated, and working in phases are just a few strategies that can help reduce the intensity of Herxheimer reactions.


In this blog, we’ll explore what a Herxheimer reaction is, why it occurs, how to differentiate it from adverse effects, and specific actions you can take to reduce discomfort. With the right approach, you can navigate these challenges and continue moving toward clearer, healthier skin.


What Is a Herxheimer Reaction or a Healing Crisis in Eczema?


Dr. Karl Herxheimer

The Herxheimer reaction describes a temporary worsening of symptoms that occurs when the body is eliminating harmful substances, such as bacteria, yeast, or toxins, at a faster rate than it can clear them. This reaction is common when addressing chronic conditions caused by underlying infections or imbalances.


Why Is It Called a Herxheimer Reaction?

The reaction is named after Karl Herxheimer, a German dermatologist who first described it in 1902. Dr. Herxheimer noticed that patients with syphilis experienced a sudden worsening of symptoms after being treated with antibiotics. He and his colleague, Dr. Adolf Jarisch, studied this phenomenon, which is why it’s sometimes called the Jarisch-Herxheimer reaction.


Their work highlighted how the rapid destruction of pathogens can overwhelm the body temporarily, triggering an inflammatory response.


What Causes a Herxheimer Reaction?

A Herxheimer reaction occurs when harmful microbes like bacteria, yeast, or parasites die off quickly in response to treatment. This “die-off” releases toxins and inflammatory compounds into the bloodstream, which the body must process and eliminate.


In eczema healing, a Herxheimer reaction may happen during treatments that target root causes, such as:

  • Gut infections (e.g., bacterial overgrowth, Candida overgrowth)

  • Detoxification protocols (e.g., liver support, toxin elimination)

  • Immune system activation (e.g., addressing underlying imbalances)


Symptoms of a Herxheimer Reaction

Herxheimer reactions can vary in intensity and duration, but common symptoms include:


  • Increased eczema flares (redness, itching, swelling)

  • Flu-like symptoms (fever, chills, body aches)

  • Fatigue or brain fog

  • Headaches

  • Digestive upset

  • Mood changes (irritability, anxiety)


While these symptoms can be unpleasant, they are usually short-lived, lasting anywhere from a few hours to a few weeks.


How to Differentiate Between Healing Reactions and Adverse Effects



It’s important to distinguish between a normal healing reaction and an adverse reaction, which may indicate a need to adjust your protocol. Here’s how they differ:

Healing Reaction

Adverse Reaction

Temporary worsening of existing symptoms

New, severe, or dangerous symptoms

Symptoms improve after a few days/weeks

Symptoms worsen progressively

Flu-like or detox-related symptoms

Allergic reactions or side effects

If you’re unsure, it’s always better to consult your healthcare provider to ensure your treatment is appropriate.


Can You Prevent a Herxheimer Reaction or Healing Crisis in Eczema?



While not every Herxheimer reaction can be entirely avoided, there are ways to minimize the likelihood and severity of these reactions. At Cleanbody, we take a gradual and comprehensive approach to healing to reduce the chances of a Herxheimer reaction. By working in phases and addressing the root causes methodically, we support the body’s natural detoxification and healing processes.


Here’s our 4-Phase Cleanbody Approach:


  1. Phase 1: Support Core Organs and Address Deficiencies

    • We start by identifying and supporting deficiencies in nutrients, digestion, and energy production. This strengthens the foundation of your health to prepare the body for deeper cleansing.

  2. Phase 2: Support Drainage Organs

    • Next, we optimize the function of drainage organs, such as the liver, kidneys, skin, and lymphatic system, ensuring that your body can eliminate toxins effectively and safely.

  3. Phase 3: Cleanse

    • Only after the body is well-supported do we begin targeted cleansing of toxins, pathogens, and other root causes of inflammation. This step is done gradually to minimize discomfort and allow the body to keep up with the detoxification process.

  4. Phase 4: Cleanbody for Life

    • Finally, we focus on maintaining long-term health through lifestyle, diet, and continued support of the body’s natural detox systems. This phase helps you stay symptom-free and resilient.


By following this step-by-step approach, we can often prevent or significantly reduce the severity of Herxheimer reactions, ensuring that your healing journey is as smooth and comfortable as possible.


How to Manage a Herxheimer Reaction or Healing Crisis


  • Hydration Is Key

    • Drink plenty of water to support your kidneys and help flush out toxins.

  • Support Your Detox Pathways

    • Liver: Use supplements like milk thistle or glutathione.

    • Skin: Try Epsom salt baths or dry brushing.

    • Gut: Incorporate fiber and probiotics to support elimination.

  • Slow Down the Protocol

    • If symptoms are intense, consider reducing the dose of your treatment or supplements. Work with a healthcare provider to adjust your protocol as needed.

  • Rest and Listen to Your Body

    • Fatigue is a common part of the healing process. Prioritize rest to give your body the energy it needs to recover.

  • Soothe Your Skin

    • Manage increased eczema flares with natural remedies such as:

      • CleanSKIN Topical Kit

      • Soakness Bath

      • Cooling compresses

  • Track Your Symptoms

    • Keep a journal to note what triggers your reactions and how long they last. This can help you and your provider tailor your approach.








When to Seek Help For a Herxheimer Reaction or Healing Crisis



While Herxheimer reactions are typically temporary and a sign of progress, consult your healthcare provider if you experience:


  • Severe or prolonged symptoms

  • Difficulty breathing or swelling (potential allergic reaction)

  • Extreme fatigue or dehydration


The Healing Crisis: A Sign of Progress

A Herxheimer reaction, while uncomfortable, is often a positive sign that your body is actively working to heal. By addressing the root causes of eczema with a step-by-step approach, you’re setting the stage for long-term relief and healthier skin.


Remember, healing is a journey that takes time. If you’re experiencing a Herxheimer reaction, know that it’s a temporary part of the process and a step toward a brighter, eczema-free future.


Take the Next Step: Discover Your Root Causes and Book a Consultation

If you’re struggling with TSW or eczema, understanding your unique root causes is the key to long-term healing. At Cleanbody, we offer the Eczema Root Cause Assessment, which helps identify the factors contributing to your eczema. With this personalized insight, you can take the first step toward regaining control of your skin health.


Take the assessment today to learn more, or click here to book a consultation and use the code BLOG10 to get 10% off, and start your healing journey!



Got Questions?

Dr. Fong is going live to discuss this topic on her weekly Live with the Eczema Doc on Wednesday, January 8, at 12:30 PM PST! Watch the live or check out the replay here:


About the Author:


Dr. Diane Angela Fong, ND, is the CEO and founder of Cleanbody, a wellness company dedicated to treating and preventing chronic disease. She is the creator of the Cleanbody Method, which follows a three-step process: Evaluate (digging into the root causes of chronic disease using lab testing and other evaluation tools), Optimize (enhancing health foundations by addressing nutrition, lifestyle, and toxic exposures), and Support (optimizing organ functions through healing protocols).


Affiliate & Product Disclaimer: This blog contains affiliate links and mentions of Cleanbody products. As an affiliate, we may earn a commission if you make a purchase through these links. However, please note that the inclusion of affiliate links does not influence our editorial content or product recommendations. Our primary goal is to provide valuable information and resources to our readers to support their health and wellness journey. We only recommend products and services that we genuinely believe in and that align with our commitment to promoting holistic health. Thank you for your support!


Medical Disclaimer: The information provided in this blog post is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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